Author

George Lambrinidis

National and Kapodistrian University of AthensORCID 0000-0002-2820-9338Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:experimental assay· 1

Frequent Co-Authors

Emmanuel MikrosiD· 3 shared George DiallinasiD· 3 shared Georgia F. PapadakiiD· 2 shared Andreas ZamanosiD· 1 shared Anezia KourkoulouiD· 1 shared Argyris PolitisiD· 1 shared Bernadette ByrneiD· 1 shared Euan PyleiD· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMolecular Biology

Emmanuel MikrosORCID

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3 papers

Recent·Most cited

Uracil/H+ symport by the FurE transporter challenges the rocking-bundle mechanism of transport in APC transporters

Iliana Zantza, Georgia F. Papadaki, Stefano Raniolo, Yiannis Pyrris, George Lambrinidis, Vittorio Limongelli, George Diallinas, Emmanuel Mikros

This study reveals the transport mechanism of uracil/H+ by FurE, showing a step-wise, induced-fit process rather than the rocking-bundle mechanism.

bioRxiv · Mar 28, 2022 · PreprintMolecular Biology

Distinct specific interactions of the UapA transporter with membrane lipids are critical for dimerization, ER-exit and function

Anezia Kourkoulou, Pothos Grevias, George Lambrinidis, Euan Pyle, Mariangela Dionysopoulou, Argyris Politis, Emmanuel Mikros, Bernadette Byrne, George Diallinas

This paper identifies lipid interactions critical for UapA dimerization and function, and shows how mutations can restore these interactions in a mammalian transporter.

bioRxiv · Jul 22, 2019 · PreprintGenetics

Cytosolic termini of the FurE transporter regulate endocytosis, pH-dependent gating and specificity

Georgia F. Papadaki, George Lambrinidis, Andreas Zamanos, Emmanuel Mikros, George Diallinas

The paper identifies motifs in the cytosolic termini of FurE that regulate endocytosis, pH-dependent gating, and substrate specificity through dynamic interactions.

bioRxiv · Mar 25, 2019 · PreprintMolecular Biology