Euan Pyle

Super-Resolution Processing Enables In Situ Subtomogram Averaging Beyond the Nyquist Limit

This paper demonstrates that super-resolution processing of electron-event representation data can recover biologically meaningful information beyond the physical Nyquist limit in in situ subtomogram averaging.

PinCorr: A high-pressure freezing carrier with intrinsic landmarks for cryo-correlative light and electron microscopy

PinCorr is a high-pressure freezing carrier with built-in landmarks that enable reliable spatial referencing for cryo-correlative light and electron microscopy.

An Advanced Mobile Laboratory to enable field-based microbial ecology and cell biology across scales

The paper introduces an Advanced Mobile Laboratory (AML) for field-based microbial ecology and cell biology, enabling multiscale analysis of environmental samples directly at the sampling site.

The In Situ Structure and Distribution of V-ATPase in C. elegans Apical Membrane Stacks

The paper examines the structure and distribution of V-ATPase in C. elegans apical membrane stacks using cryo-ET, showing they form clusters and acidify the cuticle.

An image processing pipeline for electron cryo-tomography in RELION-5

The paper introduces an image processing pipeline for electron cryo-tomography in RELION-5, enabling automated atomic model building from tomographic data.

Distinct specific interactions of the UapA transporter with membrane lipids are critical for dimerization, ER-exit and function

This paper identifies lipid interactions critical for UapA dimerization and function, and shows how mutations can restore these interactions in a mammalian transporter.