Author

Xupeng Hong

Rockefeller UniversityORCID 0000-0002-7091-6108Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Antonis AthanasiadisiD· 2 shared Catherine A. FreijeiD· 2 shared Charles M. RiceiD· 2 shared Chenhui Zou· 2 shared Corrine QuirkiD· 2 shared Eleftherios MichailidisiD· 2 shared Evgenia MoschogianniiD· 2 shared Georgios DangasiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Antonis AthanasiadisORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 23, 2026

The HBV basal core promoter mutation confers a replicative advantage and transcriptionally reprograms hepatocytes toward HCC subtypes

Leon Louis Seifert, Georgios Dangas, Hoyin Chu…·Ype P. de Jong

This study shows that HBV BCP mutations enhance viral replication and alter hepatocyte transcription, linking to specific HCC subtypes.

DOI 10.64898/2026.09.22.752323

humanbulk RNA-seq

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MicrobiologybioRxivPreprintJul 24, 2026

Orthogonal CRISPR screens and human liver chimeric mice identify hepatitis B virus host factors

Catherine A. Freije, Georgios Dangas, Antonis Athanasiadis…·Eleftherios Michailidis

The paper identifies HBV host factors using CRISPR screens and human liver chimeric mice, finding that EXOC1 is antiviral and ZCCHC14 is proviral.

DOI 10.64898/2026.07.23.740386

humangenetic perturbation / CRISPR

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