NeuroscienceJournal of Neuroimmune PharmacologyPeer-reviewed
Inhibition of the Dead Box RNA Helicase 3 prevents HIV-1 Tat and cocaine-induced neurotoxicity by targeting microglia activation
Marina V Aksenova, Justin Sybrandt, Biyun Cui…·Michael S. Shtutman
This study identifies DDX3 inhibition as a potential therapy for HAND by blocking Tat and cocaine-induced microglial activation and neurotoxicity in rat and mouse models.