Christopher T. Boughter

CountASAP converts ASAPseq FASTQ data into count matrices for downstream analysis.

This study compares the early single-cell transcriptional responses to live attenuated and inactivated Yellow Fever vaccines in mice, identifying distinct kinetic patterns and differential gene expression.

This paper introduces AIMS, a tool for analyzing immunopeptidomic datasets to identify biophysical signatures and generate machine learning models for classification.

The paper shows macrophages use TLR4 memory and IL-10 susceptibility gating to adjust inflammation based on pathogen dynamics.