Moderated designs can balance between batch-effect mitigation and cell loss due to hashtag-assisted pooling in single-cell experiments
Budhaditya Chatterjee, Katrina Gorga, Carly Blair…·Nevil J. Singh
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University of Maryland, BaltimoreORCID 0000-0001-7240-0108Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Budhaditya Chatterjee, Katrina Gorga, Carly Blair…·Nevil J. Singh
Elizabeth M. Hill, Jaclyn Bredenkamp, Gabrielle C McBroom…·Nevil J. Singh
The paper identifies VCP inhibition and calcium flux as mechanisms enabling stromal cells to secrete the IL-12 p35 subunit, regulating localized cytokine activity.
Christopher T. Boughter, Budhaditya Chatterjee, Yuko Ohta…·Martin Meier‐Schellersheim
CountASAP converts ASAPseq FASTQ data into count matrices for downstream analysis.
Budhaditya Chatterjee, Christopher T. Boughter, Katrina Gorga…·Nevil J. Singh
This study compares the early single-cell transcriptional responses to live attenuated and inactivated Yellow Fever vaccines in mice, identifying distinct kinetic patterns and differential gene expression.
Eldin Jašarević, Elizabeth M. Hill, Patrick J. Kane…·Tracy L. Bale
The paper shows that colonization with nonoptimal human cervicovaginal microbiota in mice leads to developmental issues and increased neonatal mortality.