Nevil J. Singh

Moderated designs can balance between batch-effect mitigation and cell loss due to hashtag-assisted pooling in single-cell experiments

Molecular adaptations of activated T-cells in an inflammation-associated schizophrenia sub-group

The paper identifies a unique T-cell inflammatory signature in AGA+ schizophrenia-related disorder patients using scRNA-seq, linking it to increased severity of negative symptoms.

The active secretion of a subunit of IL-12 by tissue cells is regulated by Valosin-Containing Protein and intracellular calcium redistribution.

The paper identifies VCP inhibition and calcium flux as mechanisms enabling stromal cells to secrete the IL-12 p35 subunit, regulating localized cytokine activity.

CountASAP: A Lightweight, Easy to Use Python Package for Processing ASAPseq Data

CountASAP converts ASAPseq FASTQ data into count matrices for downstream analysis.

Kinetic patterns of single cell gene expression discriminate between the murine cellular responses to live attenuated and inactivated Yellow Fever vaccines

This study compares the early single-cell transcriptional responses to live attenuated and inactivated Yellow Fever vaccines in mice, identifying distinct kinetic patterns and differential gene expression.