The structure of a Type III-A CRISPR-Cas effector complex reveals conserved and idiosyncratic contacts to target RNA and crRNA among Type III-A systems
Mohammadreza Paraan, Mohamed Nasef, Lucy Chou-Zheng, Sarah A. Khweis, Allyn J. Schoeffler, Asma Hatoum-Aslan, Scott M. Stagg, J.A. Dunkle
The paper presents the structure of a Type III-A CRISPR-Cas effector complex from S. epidermidis, revealing interactions with target RNA and crRNA and highlighting differences among related systems.
PLoS ONE · Jun 23, 2023Peer-reviewedMolecular Biology