Mohamed Nasef

This study identifies an alternate protease in S. pneumoniae TIGR4 that rescues ribosomal protein bL27 maturation in the absence of Prp.

This study shows that the Prp protease cleaves the N-terminal extension of ribosomal protein L27 in S. pneumoniae, and that this cleavage is essential for viability, though the extension itself is not required.

The paper presents the structure of a Type III-A CRISPR-Cas effector complex from S. epidermidis, revealing interactions with target RNA and crRNA and highlighting differences among related systems.