Author

Sarah A. Khweis

University of AlabamaORCID 0000-0002-7727-7265Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2

Frequent Co-Authors

J.A. DunkleiD· 2 shared Allyn J. SchoeffleriD· 1 shared Asma Hatoum-AslaniD· 1 shared C. E. Lewis· 1 shared Calvin PerdigaoiD· 1 shared Lucy Chou-ZhengiD· 1 shared Mason Blackburn· 1 shared Megan Pierce· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

J.A. DunkleORCID

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2 papers

Recent·Most cited

Cas10 residues lining the target RNA binding channel regulate interference by distinguishing cognate target RNA from mismatched targets

Sarah A. Khweis, Mason Blackburn, Calvin Perdigao, Megan Pierce, C. E. Lewis, J.A. Dunkle

The paper identifies Cas10 residues that distinguish cognate from mismatched target RNAs, enhancing interference specificity in Type III CRISPR systems.

RNA Biology · Feb 18, 2026Peer-reviewedMolecular Biology

The structure of a Type III-A CRISPR-Cas effector complex reveals conserved and idiosyncratic contacts to target RNA and crRNA among Type III-A systems

Mohammadreza Paraan, Mohamed Nasef, Lucy Chou-Zheng, Sarah A. Khweis, Allyn J. Schoeffler, Asma Hatoum-Aslan, Scott M. Stagg, J.A. Dunkle

The paper presents the structure of a Type III-A CRISPR-Cas effector complex from S. epidermidis, revealing interactions with target RNA and crRNA and highlighting differences among related systems.

PLoS ONE · Jun 23, 2023Peer-reviewedMolecular Biology