Author

Anja de Lange

University of Cape TownORCID 0000-0002-7117-8979Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

Hayley TomesiD· 3 shared Joseph V. RaimondoiD· 3 shared Chummy Sikalizyo SikasungeiD· 2 shared Clarissa Prazeres da CostaiD· 2 shared Katherine Ann SmithiD· 2 shared Ulrich Fabien ProdjinothoiD· 2 shared William G. C. HorsnelliD· 2 shared Brittany‐Amber JacobsiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Hayley TomesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cestode larvae excite host neuronal circuits via glutamatergic signaling.

Anja de Lange, Hayley Tomes, Joshua S Selfe, Ulrich Fabien Prodjinotho, Matthijs B Verhoog, Siddhartha Mahanty, Katherine Ann Smith, William G. C. Horsnell, Chummy Sikalizyo Sikasunge, Clarissa Prazeres da Costa, Joseph V. Raimondo

The paper investigates how cestode larvae affect neuronal activity by exciting host neuronal circuits through glutamatergic signaling, leading to seizure-like events in vitro.

eLife · Jul 4, 2025Peer-reviewedNeuroscience

Peripheral Taenia infection increases immunoglobulins in the central nervous system.

Sylvia Carina Van Belle, Anja de Lange, Hayley Tomes, Rodney Lucas, Vinogran Naidoo, Joseph V. Raimondo

The paper investigates the effects of peripheral Taenia crassiceps infection on the central nervous system in mice, finding increased immunoglobulins and blood-brain barrier permeability without proinflammatory cytokine changes.

International Journal for Parasitology · Mar 20, 2021Peer-reviewedNeuroscience

Taenia larvae possess distinct acetylcholinesterase profiles with implications for host cholinergic signalling

Anja de Lange, Ulrich Fabien Prodjinotho, Hayley Tomes, Jana Hagen, Brittany‐Amber Jacobs, Katherine Ann Smith, William G. C. Horsnell, Chummy Sikalizyo Sikasunge, Dorit Hockman, Murray E. Selkirk, Clarissa Prazeres da Costa, Joseph V. Raimondo

This study profiles acetylcholinesterase activity in Taenia solium and Taenia crassiceps larvae, showing differences in activity levels and localization, and demonstrates their ability to modulate neuronal responses to acetylcholine.

PLoS neglected tropical diseases · Dec 21, 2020Peer-reviewedNeuroscience