Author

Brittany‐Amber Jacobs

University of Cape TownORCID 0000-0002-6541-5560Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Adam Norton-SteeleiD· 1 shared Anja de LangeiD· 1 shared Carlos Ruiz PuigiD· 1 shared Chummy Sikalizyo SikasungeiD· 1 shared Clarissa Prazeres da CostaiD· 1 shared Dorit HockmaniD· 1 shared Felix ZhouiD· 1 shared Hayley TomesiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Adam Norton-SteeleORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Identifying phenotype-genotype-function coupling in 3D organoid imaging using Shape, Appearance and Motion Phenotype Observation Tool (SPOT)

Felix Zhou, Brittany‐Amber Jacobs, Adam Norton-Steele, Xiaoyue Han, Linna Zhou, Thomas M. Carroll, Carlos Ruiz Puig, Joseph Chadwick, Xiao Qin, Richard Lisle, Lewis Marsh, Helen Mary Byrne, Heather Harrington, Xin Lü

The paper develops SPOT, a tool for analyzing 3D morpho-dynamics from 2D live-cell imaging, and applies it to organoids to identify phenotype-genotype-function relationships.

Nature Communications · Aug 17, 2026Peer-reviewedCancer Biology

Taenia larvae possess distinct acetylcholinesterase profiles with implications for host cholinergic signalling

Anja de Lange, Ulrich Fabien Prodjinotho, Hayley Tomes, Jana Hagen, Brittany‐Amber Jacobs, Katherine Ann Smith, William G. C. Horsnell, Chummy Sikalizyo Sikasunge, Dorit Hockman, Murray E. Selkirk, Clarissa Prazeres da Costa, Joseph V. Raimondo

This study profiles acetylcholinesterase activity in Taenia solium and Taenia crassiceps larvae, showing differences in activity levels and localization, and demonstrates their ability to modulate neuronal responses to acetylcholine.

PLoS neglected tropical diseases · Dec 21, 2020Peer-reviewedNeuroscience