Qiang Wang

Non-mutated human tau stimulates Alzheimer's disease-relevant neurodegeneration in a microglia-dependent manner

This study shows that non-mutated human tau causes neurodegeneration in a microglia-dependent manner in a mouse model of Alzheimer's disease.

Curative levels of endogenous gene replacement achieved in non-human primate liver using programmable genomic integration

This paper demonstrates programmable genomic integration in non-human primate liver, achieving curative levels of gene expression in over 50% of liver cells.

Palmitoylation regulates neuropilin-2 localization and function in cortical neurons and conveys specificity to semaphorin signaling via palmitoyl acyltransferases

The paper shows that palmitoylation of neuropilin-2 is necessary for its localization and function in cortical neurons, and that different palmitoyl acyltransferases regulate its and neuropilin-1's roles in semaphorin signaling.