Author

Elliot P. Tague

Boston UniversityORCID 0000-0002-7129-5913Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

John T. NgoiD· 2 shared Ahmad S. KhaliliD· 1 shared Hui-Shan LiiD· 1 shared Jeffrey B. McMahaniD· 1 shared Mary J. DunlopiD· 1 shared Nathan TagueiD· 1 shared Nicole M. L. Wong· 1 shared Wilson W. WongiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersSynthetic Biology

John T. NgoORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Controlled protein activities with viral proteases, antiviral peptides, and antiviral drugs

Elliot P. Tague, Jeffrey B. McMahan, Nathan Tague, Mary J. Dunlop, John T. Ngo

The paper develops a system using viral proteases and antiviral drugs to control protein activity and gene modulation through allosteric regulation of Cre recombinase.

ACS Chemical Biology · May 4, 2023Peer-reviewedSynthetic Biology

Engineering clinically-approved drug gated CAR circuits

Hui-Shan Li, Nicole M. L. Wong, Elliot P. Tague, John T. Ngo, Ahmad S. Khalil, Wilson W. Wong

The paper develops drug-gated CAR circuits using NS3 protease domains and FDA-approved inhibitors to enhance CAR T cell therapy safety and specificity.

Cancer Cell · Sep 8, 2022Peer-reviewedSynthetic Biology