Author

Hui-Shan Li

Boston UniversityORCID 0000-0001-5310-2156Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Ahmad S. KhaliliD· 2 shared Wilson W. WongiD· 2 shared Divya V. IsraniiD· 1 shared Elliot P. TagueiD· 1 shared J. Keith JoungiD· 1 shared Jeffry D. SanderiD· 1 shared John T. NgoiD· 1 shared Keith A. GagnoniD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersSynthetic Biology

Ahmad S. KhalilORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Synthetic BiologySciencePeer-reviewedDec 15, 2022

Clinically-Driven Design of Synthetic Gene Regulatory Programs in Human Cells

Hui-Shan Li, Divya V. Israni, Keith A. Gagnon…·Ahmad S. Khalil

This paper designs synthetic gene regulatory programs for human cells that can be controlled by FDA-approved drugs and demonstrate therapeutic applications in immune cells.

176 citationstop 1%

humanCRISPR screen

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Synthetic BiologyCancer CellPeer-reviewedSep 8, 2022

Engineering clinically-approved drug gated CAR circuits

Hui-Shan Li, Nicole M. L. Wong, Elliot P. Tague…·Wilson W. Wong

The paper develops drug-gated CAR circuits using NS3 protease domains and FDA-approved inhibitors to enhance CAR T cell therapy safety and specificity.

116 citationstop 1%

humanexperimental assay

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