Mariana G. Pinho

This paper evaluates how reducing image resolution affects deep learning performance in bioimage segmentation, finding that lower resolution can improve accuracy or cause minimal degradation.

mAIcrobe provides an open-source framework for bacterial image analysis using deep learning models, enabling analysis of diverse bacterial species and microscopy modalities.

This paper uses FLIM-FRET to visualize FtsW protein interactions in live Staphylococcus aureus, revealing self-interactions and interactions with PBP1 and DivIB, and showing how antibiotics affect these interactions.

This study investigates how BAY 11-7082 enhances the effectiveness of certain β-lactam antibiotics against MRSA by targeting mechanisms distinct from known adjuvants.

This study investigates how S. aureus traverses nanoscale channels in bone, finding that fluid pressure, not cell division, enables bacterial entry into narrow spaces.

This study identifies RicO as a protein that anchors replication origins to the membrane in S. aureus, ensuring proper chromosome segregation.

This study investigates chromosome segregation dynamics in Staphylococcus aureus using FROS, revealing uncoupling between cell cycle and replication, and identifying key roles for SMC-ScpAB and other proteins in chromosome organization.

The paper shows Dilp8 promotes developmental stability in Drosophila by inducing oscillatory activity in PIL/GCL neurons through Lgr3 signaling and Cyclin A.