Mechanofiltration Enables High-Throughput Measurements of Bacterial Cell Mechanics
Kelsey G. DeFrates, Jae Won Hwang, Gissell Jimenez, Kerwyn Casey Huang, Joanne N. Engel, Christopher J. Hernandez
This paper introduces mechanofiltration, a high-throughput method to measure bacterial cell mechanics using standard lab equipment, showing it accurately detects changes in cell stiffness across genetic and environmental conditions.
bioRxiv · Sep 3, 2026 · PreprintMicrobiology