A cell-based scrambling assay reveals phospholipid headgroup preference of TMEM16F on the plasma membrane
Chin Fen Teo, Sami T. Tuomivaara, Niek van Hilten, David Crottès, Yuh Nung Jan, Michael Grabe, Lily Yeh Jan
The paper develops a cell-based phospholipid scrambling assay to show that TMEM16F preferentially scrambles phosphatidylserine and phosphatidylcholine over phosphatidylethanolamine.
bioRxiv · Jun 25, 2025 · PreprintCell Biology