Yuh Nung Jan

The paper develops a method to profile synaptic proteomes under physiological conditions and identifies EGFR signaling as a key activity-dependent process at synapses.

The paper identifies an atypical axon overgrowth followed by pruning in Drosophila dopamine neurons, involving AKT-GSK3β signaling and glia activity, distinct from canonical developmental remodeling.

The paper develops a cell-based phospholipid scrambling assay to show that TMEM16F preferentially scrambles phosphatidylserine and phosphatidylcholine over phosphatidylethanolamine.

The paper measures the mechanical properties of NompC gating springs and finds nonlinear compliance that may regulate mechanotransduction sensitivity.

This study develops a photo-switchable assay to study dendrite degeneration and repair in Drosophila, revealing that WldS and dSarm1 modulation affects dendrite recovery.

This study identifies a role for the Drosophila voltage-gated sodium channel, paralytic, in regulating neural progenitor proliferation and tumor suppression.

This study uses single-cell RNAseq to identify chloride channel roles in airway development, showing their impact on differentiation and disease-like defects.

The paper identifies a behavioral plasticity in male fruit flies called Shorter-Mating-Duration (SMD) and shows it depends on specific neurons, brain regions, and neuropeptide signaling.