PhysiologybioRxivPreprint
Endothelial lipase facilitates low-density lipoprotein (LDL) uptake in LDL receptor deficiency by a heparan sulfate proteoglycan-dependent mechanism.
Olivia White, Zahra Aligabi, Kendall H. Burks…·Diego Lucero
This study shows endothelial lipase (EL) enables LDL uptake in LDLR-deficient cells via heparan sulfate proteoglycans, highlighting a new pathway for LDL cholesterol reduction.
3 citations