A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells
José Maria Moreira Dias, Zhanna Alekseenko, Ashwini Jeggari, Marcelo Boareto, Jannik Vollmer, M. N. Kozhevnikova, Hui Wang, Michael P. Matise, Andrey Alexeyenko, Dagmar Iber, Johan Ericson
The paper identifies a Shh/Gli-driven three-node timer motif that controls the sequential generation of motor neurons and serotonergic neurons in the brainstem.
Science Advances · Sep 16, 2020Peer-reviewedDevelopmental Biology