Decoding spatiotemporal gene expression of the developing human spinal cord and implications for ependymoma origin
Xiaofei Li, Žaneta Andrusivová, Paulo Czarnewski, Christoffer Mattsson Langseth, Alma Andersson, Yang Liu, Daniel Gyllborg, Emelie Braun, Ludvig Larsson, Lijuan Hu, Zhanna Alekseenko, Hower Lee, Christophe Avenel, Helena Kopp Kallner, Elisabet Åkesson, , Erik Sundström
The paper creates a developmental cell atlas of the human spinal cord using single-cell and spatial transcriptomics, revealing spatiotemporal gene regulation and novel insights into ependymoma cancer stem cells.
Nature Neuroscience · Apr 24, 2023Peer-reviewedDevelopmental Biology