Johan Ericson

The paper challenges the traditional view that morphogen concentration fluctuations determine transition zone width, showing instead that cellular readout noise is the key factor.

This paper describes a protocol to generate human posterior axial assembloids from pluripotent stem cells, demonstrating multi-lineage differentiation and tissue complexity.

The paper identifies a Shh/Gli-driven three-node timer motif that controls the sequential generation of motor neurons and serotonergic neurons in the brainstem.