Soichiro Kawagoe

OptoChaperone enables reversible, spatiotemporal control of protein condensates using light, demonstrating efficacy in regulating disease-related condensates without chemical additives or genetic modifications.

This study investigates how the K76E mutation in PPIA affects protein dynamics and function, finding that it impairs isomerase activity through allosteric network disruption rather than structural changes.

This study identifies HSF5 as a male germ cell-specific factor critical for meiotic prophase progression beyond pachytene under non-stress conditions.