In the Drosophila germline H2Av and Arp6 suppress transposons by driving piRNA pathway expression
Norbert Andrási, Hannah M Ryon, Yicheng Luo, Katalin Fejes Tóth
This study shows that Arp6 and H2Av maintain genomic stability in Drosophila by promoting piRNA pathway gene transcription, which is essential for suppressing transposable elements in the germline.
bioRxiv · May 21, 2026 · PreprintMolecular Biology