Katalin Fejes Tóth

This study shows that Arp6 and H2Av maintain genomic stability in Drosophila by promoting piRNA pathway gene transcription, which is essential for suppressing transposable elements in the germline.

The paper shows that SetDB1 auto-methylation at histone-mimic motifs enables heterochromatin spreading and maintenance through interactions with HP1 proteins.

The paper shows maternally inherited siRNAs trigger de novo formation of piRNA clusters in Drosophila, which then sustain themselves without ongoing siRNA input.

The paper identifies SUMOylation targets in Drosophila ovary, revealing its role in heterochromatin regulation and piRNA pathway function.

This study identifies Bonus, a Drosophila TIF1 homolog, as a repressor of tissue-specific genes through SUMOylation-dependent recruitment of repressive chromatin complexes.

This study shows that the piRNA pathway, via Piwil1, regulates epithelial-to-mesenchymal transition in chick neural crest cells by controlling Sox2 expression.

The paper shows that Su(var)2-10 regulates gene expression in euchromatin and heterochromatin by establishing H3K9me3 and providing negative feedback.

This study shows that SUMO and Su(var)2-10 are required for piRNA-guided chromatin silencing in Drosophila by linking target recognition to histone methyltransferase recruitment.