The RAB27A effector SYTL5 regulates mitophagy and mitochondrial metabolism
Ana Lapão, Lauren Sophie Johnson, Laura Trachsel-Moncho, Samuel J. Rodgers, Sakshi Singh, MATTHEW MA‐TAI NG, Sigve Nakken, Eeva‐Liisa Eskelinen, Anne Simonsen
This study identifies SYTL5 as a RAB27A effector that regulates mitophagy and mitochondrial metabolism, with reduced expression linked to poor survival in adrenocortical carcinoma.
bioRxiv · Dec 30, 2024Cell Biology