Author

Laura Trachsel-Moncho

Oslo University HospitalORCID 0000-0002-8525-7790Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1 Organism:zebrafish· 1

Frequent Co-Authors

Anne SimonseniD· 3 shared Ana LapãoiD· 2 shared Chiara VeroniiD· 2 shared Nagham Theres AspiD· 2 shared Sakshi SinghiD· 2 shared Arja Arnesen Løchen· 1 shared Benan John MathaiiD· 1 shared Eeva‐Liisa EskelineniD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCell Biology

Anne SimonsenORCID

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3 papers

Recent·Most cited

Interaction of HS1BP3 with cortactin modulates TKS5 localisation and cancer malignancy

Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel-Moncho, Nagham Asp, Robin Gaupset, Helene Knævelsrud, Lars Lohne Eftang, Anne Simonsen

The paper shows HS1BP3 interacts with cortactin's SH3 domain, affecting TKS5 localization and cancer progression in gastric and breast cancers.

bioRxiv · Jul 14, 2025 · PreprintCell Biology

SNX10 functions as a modulator of piecemeal mitophagy and mitochondrial bioenergetics

Laura Trachsel-Moncho, Chiara Veroni, Benan John Mathai, Ana Lapão, Sakshi Singh, Nagham Theres Asp, Sebastian Wolfgang Schultz, Serhiy Pankiv, Anne Simonsen

This study identifies SNX10 as a negative regulator of piecemeal mitophagy and mitochondrial bioenergetics, showing its role in modulating mitochondrial homeostasis and cell survival.

The Journal of Cell Biology · Feb 5, 2025Peer-reviewedCell Biology

The RAB27A effector SYTL5 regulates mitophagy and mitochondrial metabolism

Ana Lapão, Lauren Sophie Johnson, Laura Trachsel-Moncho, Samuel J. Rodgers, Sakshi Singh, MATTHEW MA‐TAI NG, Sigve Nakken, Eeva‐Liisa Eskelinen, Anne Simonsen

This study identifies SYTL5 as a RAB27A effector that regulates mitophagy and mitochondrial metabolism, with reduced expression linked to poor survival in adrenocortical carcinoma.

bioRxiv · Dec 30, 2024Cell Biology