Author

Roger Cachope

CHDI FoundationORCID 0000-0002-7217-0119Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:imaging· 4 Organism:mouse· 4 Approach:statistical model· 4 Research Focus:spatial domain detection· 3 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Annemie Van der LindeniD· 4 shared Dorian PustinaiD· 4 shared Marleen VerhoyeiD· 4 shared Tamara VasilkovskaiD· 4 shared Haiying Tang· 3 shared Ignacio Muñoz-SanjuániD· 3 shared Johan Van AudekerkeiD· 3 shared Mohit H. AdhikariiD· 3 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersNeuroscience

Annemie Van der LindenORCID

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4 papers

Recent·Most cited

Mapping brain volume changes in the zQ175DN mouse model of Huntington's disease: a longitudinal MRI study

Nicholas Vidas-Guscic, Tamara Vasilkovska, Stefanie Pluym, Joëlle van Rijswijk, Johan Van Audekerke, Haiying Tang, Ignacio Muñoz-Sanjuán, Dorian Pustina, Roger Cachope, Annemie Van der Linden, Daniele Bertoglio, Marleen Verhoye

This study uses longitudinal MRI to analyze brain volume changes in zQ175DN mice, finding early striatal atrophy and later cortical and corpus callosum reductions similar to human HD.

Biomarker Research · Sep 1, 2026Peer-reviewedNeuroscience

Evolution of aberrant brain-wide spatiotemporal dynamics of resting-state networks in a Huntington's disease mouse model

Tamara Vasilkovska, Marlies Verschuuren, Dorian Pustina, Monica van den Berg, Johan Van Audekerke, Isabel Pintelon, Roger Cachope, Winnok Harald De Vos, Annemie Van der Linden, Mohit H. Adhikari, Marleen Verhoye

This study investigates altered spatiotemporal dynamics of resting-state networks in a Huntington's disease mouse model using dynamic functional connectivity and identifies age- and genotype-specific quasi-periodic patterns of brain activity.

Clinical and Translational Medicine · Oct 1, 2024Peer-reviewedNeuroscience

Longitudinal investigation of changes in resting-state co-activation patterns and their predictive ability in the zQ175 DN mouse model of Huntington's disease

Mohit H. Adhikari, Tamara Vasilkovska, Roger Cachope, Haiying Tang, Longbin Liu, Georgios A. Keliris, Ignacio Muñoz-Sanjuán, Dorian Pustina, Annemie Van der Linden, Marleen Verhoye

The paper investigates changes in resting-state co-activation patterns in a Huntington's disease mouse model and finds they predict disease states with high accuracy.

Scientific Reports · Jun 23, 2023Peer-reviewedNeuroscience

Resting-State fMRI reveals Longitudinal Alterations in Brain Network Connectivity in a Mouse Model of Huntington's Disease

Tamara Vasilkovska, Mohit H. Adhikari, Johan Van Audekerke, Dorian Pustina, Roger Cachope, Haiying Tang, Longbin Liu, Ignacio Muñoz-Sanjuán, Annemie Van der Linden, Marleen Verhoye

This study uses resting-state fMRI to track longitudinal changes in brain network connectivity in a mouse model of Huntington's disease, revealing age-related alterations in cortical and subcortical networks.

bioRxiv · Nov 19, 2022 · PreprintNeuroscience