Marlies Verschuuren

Evolution of aberrant brain-wide spatiotemporal dynamics of resting-state networks in a Huntington's disease mouse model

This study investigates altered spatiotemporal dynamics of resting-state networks in a Huntington's disease mouse model using dynamic functional connectivity and identifies age- and genotype-specific quasi-periodic patterns of brain activity.

Systematic quantification of synapses in primary neuronal culture

The paper develops a proximity ligation-based method to improve synapse quantification in neuronal cultures by reducing false positives and increasing sensitivity.

Deep coverage microscopy exposes a pharmacological window for modifiers of neuronal network connectivity

The paper develops a microscopy-based pipeline to quantify neuronal network connectivity and identifies compounds that enhance connectivity and provide neuroprotection.