Dietary fructose promotes MASH/HCC progression through enhanced intestinal HIF-2α-dependent iron absorption
Robert A. Mitchell, Manman Xu, Elizabeth Hudson, Madison S. Taylor, Bradford G. Hill, Craig James McClain, Ming Song
This paper shows dietary fructose promotes MASH/HCC by enhancing intestinal HIF-2α-dependent iron absorption through the KHK/PKM2/HIF-2 axis.
bioRxiv · Jun 11, 2026 · PreprintPhysiology