PathologyStem Cells InternationalPeer-reviewed
Modeling Thoracic Aortic Dissection Using Patient-Specific iPSCs Reveals VSMC Dysfunction and Extracellular Matrix Dysregulation
Peifeng Jin, Yubin Xu, Sixian Wang…·Yongyu Wang
This study uses patient-specific iPSCs to model thoracic aortic dissection, revealing VSMC dysfunction and extracellular matrix dysregulation linked to COL4A2 mutations and TGF-β signaling.