Author

Ngoc Lu‐Nguyen

Royal Holloway University of LondonORCID 0000-0002-7241-9607Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alberto MalerbaiD· 2 shared Linda J. PopplewelliD· 2 shared Alexis BoulinguieziD· 1 shared George Dickson· 1 shared James MarchiD· 1 shared Jessica TrundleiD· 1 shared Shan Herath· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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2 shared papersPathology

Alberto MalerbaORCID

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2 papers

Recent·Most cited

PathologybioRxivPreprintJan 21, 2025

Periostin exon 17 skipping enhances the efficacy of local AAV-microdystrophin administration in a fibrotic model of Duchenne muscular dystrophy

Jessica Trundle, Alexis Boulinguiez, Ngoc Lu‐Nguyen…·Linda J. Popplewell

This study shows that periostin exon 17 skipping combined with AAV-microdystrophin improves muscle function and microdystrophin expression in a fibrotic DMD model.

1 citation

mousebulk RNA-seq

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Molecular BiologyHuman Molecular GeneticsPeer-reviewedMay 11, 2021

Systemic antisense therapeutics inhibiting DUX4 expression improves muscle function in an FSHD mouse model

Ngoc Lu‐Nguyen, Alberto Malerba, Shan Herath…·Linda J. Popplewell

This study shows that systemic antisense therapy targeting DUX4 improves muscle function in an FSHD mouse model by reducing DUX4 expression and associated pathology.

32 citations

mouseexperimental assay

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