Author

Thomas Holowka

University of North Carolina at Chapel HillORCID 0000-0002-7244-6314Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alisher Bimagambetov· 1 shared David van DuiniD· 1 shared Jamie Xiao· 1 shared Jason W. ArnoldiD· 1 shared Jonathan Richard SwanniD· 1 shared Kalisvar MarimuthuiD· 1 shared Kenneth Walsh· 1 shared Luther A. BarteltiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Alisher Bimagambetov

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1 paper

Recent·Most cited

Protein Malnutrition Facilitates Intestinal Colonization with Highly Resistant Klebsiella pneumoniae

Thomas Holowka, Veronica Feijoli Santiago, Jamie Xiao, Mera F. Liccione, Alisher Bimagambetov, Kenneth Walsh, Jason W. Arnold, Kalisvar Marimuthu, Oon Tek Ng, Jonathan Richard Swann, David van Duin, Luther A. Bartelt

This study shows that protein malnutrition in mice increases susceptibility to intestinal colonization by carbapenem-resistant Klebsiella pneumoniae, likely through reduced secondary bile acids.

bioRxiv · Jul 21, 2025 · PreprintMicrobiology