Bona fide cytotoxic iNKT cells with superior antitumour responses identified in mice and humans
Carolina de Amat Herbozo, Stephanie WY Wong, Meggie Kuypers, Guy Ilango, Zhewei Liu, Jessica A. Mathews, Albert Nguyen, André Veillette, Jennifer L. Gommerman, Thomas Baranek, Sarah Q. Crome, Ming‐Sound Tsao, Adrian G. Sacher, Christophe Paget, Thierry Mallevaey
This study identifies specific iNKT cell subsets in mice and humans with enhanced antitumor activity, suggesting potential improvements for adoptive cell therapies.
bioRxiv · Jul 18, 2024 · PreprintImmunology