Author

Jessica E. Buddle

University of SheffieldORCID 0000-0002-7259-0527Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Robert P. FaganiD· 2 shared Abigail R. E. RobertsiD· 1 shared Ainhoa Dafis-SagarmendiiD· 1 shared Claire E. TurneriD· 1 shared Franziska FaberiD· 1 shared Harold W. FisheriD· 1 shared Jamie K. HobbsiD· 1 shared Joseph A. KirkiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Robert P. FaganORCID

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2 papers

Recent·Most cited

Protein architectures of the bacterial spore envelope - common principles of assembly

Harold W. Fisher, Abigail R. E. Roberts, Ainhoa Dafis-Sagarmendi, Nic Mullin, Jessica E. Buddle, Thamarai K. Janganan, Jamie K. Hobbs, Robert P. Fagan, Per A. Bullough

The paper investigates the structural organization and assembly of the bacterial spore envelope in Clostridium sporogenes, revealing common principles of crystalline and disulphide-based self-assembly across distantly related bacteria.

bioRxiv · Sep 7, 2026 · PreprintMicrobiology

A novel two-component system controls vancomycin resistance in epidemic Clostridioides difficile

Jessica E. Buddle, Victoria K Pennington, Joseph A. Kirk, Franziska Faber, Claire E. Turner, Michael A. Brockhurst, Robert P. Fagan

This paper identifies two point mutations in a two-component system that confer vancomycin resistance in C. difficile, revealing a synergistic pathway for resistance in epidemic strains.

bioRxiv · Aug 21, 2025 · PreprintMicrobiology