Author

Pauline Lanting

University Medical Center GroningenORCID 0000-0002-7288-4445Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Approach:statistical model· 3 Assay:GWAS summary statistics· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Lude FrankeiD· 4 shared Patrick DeeleniD· 3 shared Cisca WijmengaiD· 2 shared Esteban A. Lopera-MayaiD· 2 shared Lifelines Cohort Study· 2 shared Robert WarmerdamiD· 2 shared Adelita V. RanchoriD· 1 shared Adriaan van der GraafiD· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersGenetic & Genomic Medicine

Lude FrankeORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Idefix: identifying accidental sample mix-ups in biobanks using polygenic scores

Robert Warmerdam, Pauline Lanting, Lifelines Cohort Study, Patrick Deelen, Lude Franke

Idefix identifies sample mix-ups in biobanks using polygenic scores, achieving an AUC of 0.90 compared to 0.75 with sex alone.

Bioinformatics · Nov 15, 2021Peer-reviewedBioinformatics

Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility

Irene V. van Blokland, Pauline Lanting, Anil P. S. Ori, Judith M. Vonk, Robert Warmerdam, Johanna C. Herkert, Floranne Boulogne, Annique Claringbould, Esteban A. Lopera-Maya, Meike Bartels, Jouke‐Jan Hottenga, Andrea Ganna, Juha M Karjalainen, Lifelines COVID-19 cohort study, The COVID-19 Host Genetics Initiative, , Lude Franke

The paper uses symptom-based case predictions to conduct a GWAS on COVID-19, finding new genetic susceptibility insights and suggesting different genetic architectures for severity and susceptibility.

PLoS ONE · Aug 11, 2021Peer-reviewedGenetic & Genomic Medicine

Practical barriers and facilitators experienced by patients, pharmacists and physicians to the implementation of pharmacogenomic screening in Dutch outpatient hospital care - an explorative pilot study

Pauline Lanting, Evelien Drenth, Ludolf G. Boven, Amanda van Hoek, Annemiek Hijlkema, Ellen Poot, Gerben B. van der Vries, Robert A. Schoevers, Ernst Horwitz, Rijk O. B. Gans, Jos G. W. Kosterink, Mirjam Plantinga, Irene M. van Langen, Adelita V. Ranchor, Cisca Wijmenga, , Rolf H. Sijmons

This study identifies barriers and facilitators to implementing pharmacogenomic screening in Dutch outpatient care through stakeholder perspectives.

Journal of Personalized Medicine · Dec 21, 2020Peer-reviewedGenetic & Genomic Medicine

Lack of association between genetic variants at ACE2 and TMPRSS2 genes involved in SARS-CoV-2 infection and human quantitative phenotypes

Esteban A. Lopera-Maya, Adriaan van der Graaf, Pauline Lanting, Marije van der Geest, Lifelines Cohort Study, Jingyuan Fu, Morris Swertz, Lude Franke, Cisca Wijmenga, Patrick Deelen, Alexandra Zhernakova, Serena Sanna

This study investigates genetic variants in ACE2 and TMPRSS2 genes for associations with quantitative phenotypes and medication use in a population cohort, finding suggestive links with hypertension and inflammation-related drugs.

Frontiers in Genetics · Jun 8, 2020Peer-reviewedGenetic & Genomic Medicine