Owen D. Jones

Synaptic plasticity deficits via aberrant engagement of metaplasticity in the hippocampus of PS19 mice

This study examines synaptic plasticity and neuroinflammation in the hippocampus of PS19 mice, revealing region-specific synaptic deficits and altered metaplasticity.

GLP-1 agonism alters local field potential in the lateral septum and alters operant behavior in rats

This study shows that GLP-1 agonism affects lateral septum activity and operant behavior in rats, suggesting a central role for this brain region in reward processing.

Absence of homeostatic downscaling in dentate gyrus granule cells

The paper investigates homeostatic downscaling in dentate gyrus granule cells and finds no evidence of reduced synaptic input or intrinsic excitability after prolonged GABAA receptor blockade.

Astrocyte Ca2+ signalling mediates long-distance metaplasticity in the hippocampal CA1

The paper shows astrocyte Ca2+ signaling mediates long-distance metaplasticity in hippocampal CA1 by involving adenosine A2B receptors, tumor necrosis factor, and GluN2B-containing NMDA receptors.