Shruthi Sateesh

The paper demonstrates transregional astrocyte-dependent metaplasticity in the hippocampus, showing that SO priming inhibits LTP in DG MML synapses via astrocytic TNF signaling and GluN2B receptor activation.

This study examines synaptic plasticity and neuroinflammation in the hippocampus of PS19 mice, revealing region-specific synaptic deficits and altered metaplasticity.

The paper shows astrocytes supply co-agonists for LTP induction at different hippocampal synapses, with glycine for MPP-DG and D-serine for SC-CA1.

This study shows that reduced FMRP expression in Syngap1+/− mice leads to increased Syngap1 translation and altered eEF2 phosphorylation via NMDA receptor signaling.