Wickliffe C. Abraham

The paper demonstrates transregional astrocyte-dependent metaplasticity in the hippocampus, showing that SO priming inhibits LTP in DG MML synapses via astrocytic TNF signaling and GluN2B receptor activation.

This study examines synaptic plasticity and neuroinflammation in the hippocampus of PS19 mice, revealing region-specific synaptic deficits and altered metaplasticity.

This study shows that the superior colliculus gates dopamine responses to conditioned stimuli in visual classical conditioning by developing neuronal responses to the CS and requiring convergence of visual, dopamine, and serotonin inputs.

The paper investigates homeostatic downscaling in dentate gyrus granule cells and finds no evidence of reduced synaptic input or intrinsic excitability after prolonged GABAA receptor blockade.

This study investigates how perisynaptic astroglia interact with synapses during long-term potentiation and depression in the hippocampal dentate gyrus of rats.

The paper shows astrocytes supply co-agonists for LTP induction at different hippocampal synapses, with glycine for MPP-DG and D-serine for SC-CA1.

The paper introduces DunedinPACNI, a brain MRI-based aging measure that predicts dementia conversion, morbidity, and mortality.

This study shows that long-term potentiation (LTP) increases synaptic information storage capacity in adult rat hippocampus by expanding the range of synapse sizes and improving precision.

The paper shows astrocyte Ca2+ signaling mediates long-distance metaplasticity in hippocampal CA1 by involving adenosine A2B receptors, tumor necrosis factor, and GluN2B-containing NMDA receptors.

The paper examines how functional topography of neocortical networks in midlife relates to covariation in motor and cognitive abilities, finding that motor ability reflects functional topography differences while hearing does not.

The paper examines the association between retinal neuronal layer thickness and brain structural integrity in midlife, finding thinner retinal layers correlate with reduced brain structural measures.

The paper introduces a method to measure synaptic information storage capacity (SISC) using 3DEM data from rat hippocampus and finds regional and LTP-dependent variations in SISC.