Author

Weijie Gao

Westlake UniversityORCID 0000-0002-7312-785XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1

Frequent Co-Authors

Bangdong HuangiD· 2 shared Weizhi XiniD· 2 shared Yundi Hu· 2 shared Jin CheniD· 1 shared Liang Enyuan· 1 shared Qiang SuiD· 1 shared Qiang SuiD· 1 shared Qiang ZhouiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

Bangdong HuangORCID

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2 papers

Recent·Most cited

ImmunologyCell DiscoveryPeer-reviewedAug 11, 2026

Phosphoantigen-Driven Dissociation of Butyrophilin Oligomers Activates γδ T Cells

Weizhi Xin, Bangdong Huang, Weijie Gao…·Qiang Zhou

This study identifies that phosphoantigen binding causes butyrophilin oligomers to dissociate, enabling Vγ9Vδ2 TCR engagement and activation of γδ T cells.

2 citations

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

ImmunologybioRxivPreprintOct 21, 2025

Molecular Mechanisms Underlying Human Vγ9Vδ2 T Cell Activation by Butyrophilin-3 (BTN3) Targeted Antibodies

Bangdong Huang, Weizhi Xin, Wenjia Zhang…·Qiang Zhou

This study identifies how ICT01 antibody activates Vγ9Vδ2 T cells by binding BTN3As, destabilizing BTN2A1-BTN3As interface, and promoting TCR engagement.

DOI 10.1101/2025.10.21.681109

humanexperimental assay

𝕏 PostBluesky