Aneesh Deshmukh

A 3D Soft X-Ray Structural Atlas of Multicellular Cable Bacteria

This study creates a 3D structural atlas of cable bacteria using SXT and other techniques, revealing intracellular organization and conductive network features.

Morphotype-Resolved 3D Morphometry Reveals a Structure-Density-Location Coupling in Mitochondrial Networks

This study uses 3D morphometry to show how mitochondrial structure, density, and location change in response to metabolic stimuli in INS-1E cells.

Dielectrophoresis Reveals Stimulus-Induced Remodeling of Insulin Granule Subpopulations

This paper uses dielectrophoresis to separate insulin granule subpopulations and shows they change in response to insulinotropic signals.

Integrated biophysical and spatial remodeling during insulin secretory granule maturation at the mitochondrial network

The paper examines how mitochondrial proximity influences insulin secretory granule (ISG) maturation through biophysical and spatial changes in pancreatic beta cells.

Robust Deep Learning-based 3D Segmentation and Morphological Analysis of Mitochondria using Soft X-ray Tomography

The paper introduces MitoXRNet, a deep learning model for 3D segmentation of mitochondria and nuclei from soft x-ray tomography data, showing improved performance and enabling analysis of mitochondrial morphology changes under different conditions.

Classifying Biophysical Subpopulations of Insulin Secretory Granules using Quantitative Whole Cell Structure Analysis

The paper classifies insulin secretory granule subpopulations using quantitative whole-cell structure analysis and shows exogenous signals dynamically remodel their distribution.

Secretory stimuli distinctly regulate insulin secretory granule maturation through structural remodeling

This study shows secretory stimuli induce distinct structural changes in insulin secretory granules, affecting their maturation and subcellular distribution in beta-cells.