Author

Su Wu

Harvard UniversityORCID 0000-0002-7317-3389Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:deep learning· 2 Organism:plant (other)· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Gerhard WagneriD· 2 shared Anders M. Näär· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

2 top collaborators · 0 mutual co-author links

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2 shared papersBiophysics

Gerhard WagnerORCID

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintMay 14, 2025

Mechanistic Insights into the Plasmodium Phosphatase UIS2 in eIF2α Dephosphorylation via Integrated Structure-Based Modeling

Su Wu, Gerhard Wagner

This study identifies the structural basis of UIS2-mediated eIF2α dephosphorylation in Plasmodium using integrated modeling and shows how Salubrinal inhibits this process.

DOI 10.1101/2025.05.14.654012

plant (other)structural biology

𝕏 PostBluesky

BiochemistrybioRxivPreprintJun 25, 2024

Structural and mechanistic insights into Plasmodium eIF2alpha dephosphorylation by UIS2 during the erythrocytic stage

Su Wu, Gerhard Wagner

This paper identifies UIS2 as a critical phosphatase for Plasmodium proliferation during the erythrocytic stage and reveals its structural mechanism for eIF2alpha dephosphorylation, suggesting it as a target for antimalarial drugs.

DOI 10.1101/2024.06.25.600622

plant (other)bulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 11, 2018

Elevated de novo fatty acid biosynthesis gene expression promotes melanoma cell survival and drug resistance

Su Wu, Anders M. Näär

DOI 10.1101/441303

humanbulk RNA-seq

𝕏 PostBluesky