Systemic inflammation modulates the levels of EBI2 and 7α,25-OHC synthesizing (CH25H, CYP7B1) and degrading (HSD3B7) enzymes in brain microvascular cells
Fionä Caratis, Bartosz Karaszewski, Ilona Klejbor, Tomomi Furihata, Aleksandra Rutkowska
The paper investigates how systemic inflammation affects the expression of enzymes involved in 7α,25-OHC synthesis and degradation in brain microvascular cells, revealing species-specific differences between mice and humans.
bioRxiv · Apr 16, 2023 · PreprintNeuroscience