Author

Mikołaj Opiełka

Gdańsk Medical UniversityORCID 0000-0003-3423-3745Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Agnieszka MickiewicziD· 1 shared Aleksandra RutkowskaiD· 1 shared Andrzej ŁośiD· 1 shared Anna KosteckaiD· 1 shared Arkadiusz PiotrowskiiD· 1 shared Bartosz KaraszewskiiD· 1 shared Cheryl de VallièreiD· 1 shared Ewa Iżycka‐ŚwieszewskaiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCell Biology

Agnieszka MickiewiczORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 9, 2025

The effect of cold ischemia time on hypoxia, EMT, and apoptosis pathways in normal colon mucosa

Katarzyna Duzowska, Mikołaj Opiełka, Kinga Drężek-Chyła…·Natalia H. Filipowicz

This study evaluates how cold ischemia time affects gene expression in normal colon mucosa, identifying transcriptomic changes in hypoxia, EMT, and apoptosis pathways that may mimic malignancy.

DOI 10.1101/2025.03.09.642255

humanbulk RNA-seq

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Cell BiologybioRxivPreprintOct 31, 2024

Expression Profile of Human Bitter Taste Receptors in Human Aortic and Coronary Artery Endothelial Cells

Paweł Kochany, Mikołaj Opiełka, Paulina Słonimska…·Magdalena Górska‐Ponikowska

This study identifies TAS2R expression in human aortic and coronary artery endothelial cells, finding higher expression in coronary artery cells and confirming protein presence for TAS2R10 and TAS2R38.

4 citations

humanbulk RNA-seq

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NeurosciencebioRxivPreprintMar 2, 2023

The proton-activated receptor TDAG8 is upregulated in oligodendrocytes during maturation and under acidic conditions.

Mikołaj Opiełka, Fionä Caratis, Martin Hausmann…·Aleksandra Rutkowska

The paper investigates TDAG8 expression and function in oligodendrocytes under acidic conditions and inflammation, finding upregulation during maturation and in MS lesions.

DOI 10.1101/2023.03.02.530787

humanmouse

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