A single 2'-O-methylation of ribosomal RNA gates assembly of a functionalribosome
James N. Yelland, Jack P. K. Bravo, Joshua J. Black, David Ward Taylor, Alan M. Johnson
The paper shows that a single 2'-O-methylation of ribosomal RNA is essential for ribosome assembly and nuclear export, with Nog2 interacting specifically with the methylated base.
Nature Structural & Molecular Biology · Dec 19, 2022Peer-reviewedMolecular Biology