Author

John O. Trent

University of LouisvilleORCID 0000-0002-7346-4231Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Robert D. GrayiD· 2 shared Alfred Bennett Jenson· 1 shared Antonio A. Mignucci‐GiannoniiD· 1 shared Eric Christian RouchkaiD· 1 shared Gregory D. Bossart· 1 shared Jonathan B. Chaires· 1 shared Jonathan Brad ChairesiD· 1 shared Joongho J. JohiD· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Robert D. GrayORCID

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2 papers

Recent·Most cited

Identification of putative G-quadruplex forming sequences in three manatee papillomaviruses

Maryam Zahin, William L. Dean, Shin‐je Ghim, Joongho J. Joh, Robert D. Gray, Sujita Khanal, Gregory D. Bossart, Antonio A. Mignucci‐Giannoni, Eric Christian Rouchka, Alfred Bennett Jenson, John O. Trent, Jonathan Brad Chaires, Julia H. Chariker

This paper identifies G-quadruplex forming sequences in three manatee papillomaviruses using computational and biophysical analysis, suggesting their regulatory role in viral function.

PLoS ONE · Apr 9, 2018Peer-reviewedMolecular Biology

A high-throughput fluorescent indicator displacement assay and principal component/cluster data analysis for determination of ligand-nucleic acid structural selectivity

Rafael del Villar-Guerra, Robert D. Gray, John O. Trent, Jonathan B. Chaires

The paper introduces a high-throughput fluorescence indicator displacement assay combined with PCA and HCA to assess ligand selectivity for different DNA structures, showing selectivity for G4 structures in a subset of tested compounds.

bioRxiv · Sep 22, 2017 · PreprintBiophysics