Cancer BiologybioRxivPreprint
Targeting protein tyrosine phosphatase non-receptor type 2 with a novel inhibitor for AML therapy
Wenbin Kuang, Jinxin Jiang, Xiao Wang…·Peng Yang
This study identifies PTPN2 as a therapeutic target in AML, discovers a selective inhibitor K73, and demonstrates its efficacy in reducing AML burden in vitro and in vivo.
2 citations