Dylan Mooijman

The paper demonstrates that the 10x Genomics Gene Expression Flex protocol can profile mixed human and mouse cells in xenografts by using combined probe sets and a pipeline to remove cross-reactive signals.

The paper introduces a single-cell methylomics method to study DNA demethylation dynamics in early mammalian development and finds distinct active and passive demethylation modes in mouse and human embryos.

This paper introduces a method to simultaneously measure protein-DNA contacts and transcriptomes in single cells, revealing how chromatin states and genome organization influence gene expression.