Franka J. Rang

This study identifies H3K27me3's role in regulating genome-nuclear lamina interactions and allelic asymmetry during early mouse embryogenesis through single-cell LAD profiling and chromatin state analysis.

This paper introduces EpiDamID, a method to profile histone modifications and transcriptomes at single-cell resolution, and demonstrates its application in mouse and zebrafish systems.

This paper introduces a method to simultaneously measure protein-DNA contacts and transcriptomes in single cells, revealing how chromatin states and genome organization influence gene expression.